To block ads on the skype application (tested with 7.12 from 28.10.15) , you can
add the following lines to your host (file: %windir%\system32\drivers\etc\hosts) as administrator!
127.0.0.1 rad.msn.com
127.0.0.1 live.rads.msn.com
127.0.0.1 ads1.msn.com
127.0.0.1 g.msn.com
127.0.0.1 a.ads2.msads.net
127.0.0.1 b.ads2.msads.net
127.0.0.1 ac3.msn.com
If you also add the following line, as stated in some tutorials:
127.0.0.1 apps.skype.com
the skype home can not be loaded any more.